It’s a six-pointer on Sunday evening as Liverpool host Manchester City at Anfield.
The Reds already have a six point lead over their title-rivals, but a win this weekend will extend that to nine points.
Only Manchester United have taken points off Jurgen Klopp’s side this season, but they’re yet to lose a game.
Liverpool made a number of changes midweek against GENK in the Champions League, with Naby Keita, Alex Oxlade-Chamberlain among others to come into the fold.
There are few injury concerns for Klopp, who has close to a fully-fit squad to select from.
Joel Matip remains the only key omission as he recovers from injury, Xherdan Shaqiri and Nathaniel Clyne are also sidelined.
Jordan Henderson missed their 2-1 victory over the Belgian side on Tuesday night due to illness, but is fit and expected to start against City.
Manchester City’s injury woes continue, however, as Ederson joins the list of players sidelined for the League Champions.
The goalkeeper picked up a thigh injury when his side faced Atalanta in the UCL group stage on Wednesday night.
Guardiola didn’t provide any updates on Rodri or David Silva during friday’s press conference, but they too remain a doubt for Sunday’s fixture.
Long-term injures to Laporte and Sane mean they’re set to miss the Liverpool clash.
Liverpool: Alisson, Alexander-Arnold, Lovren, Van Dijk, Robertson, Fabinho, Henderson, Wijnaldum, Salah, Firmino, Mane
Man City: Bravo, Walker, Stones, Fernandinho, Mendy, Gündoğan, De Bruyne, B.Silva, Sterling, Mahrez, Aguero
What to Expect
A cagey affair
This fixture last season was not the high-scoring match of previous years – a 0-0 draw rounded off by Riyad Mahrez missing a late penalty.
Both sides appeared scared to attack, were incredibly cautious going forward in fear of leaving spaces in behind.
The same can be expected this time around with so much riding on such a big game.
A win for City would close the gap to just 3 points but a win for the Reds would extend it to nine points, which could be vital heading into the most intense period of the season.
A lively Anfield
Anfield turns into a cauldron of noise when teams like Manchester City come to town.
Fans and players alike understand the importance of such a game, it will be a far from welcoming atmosphere for Guardiola’s men.
It’s no secret that they’ve struggled facing the Merseyside club in seasons gone by, suffering a 4-2 defeat in 17/18 as well as a 3-0 loss in the Champions League.
It’s likely to be another closely-fought game on Sunday, but one Liverpool will be determined to win.
Guardiola will be taking few risks, however, so any win the Reds will have to fight for.
We’re going for another 2-1 Liverpool win, a result that’s quickly become a trend for the European Champions.